{"id":61,"date":"2022-11-28T20:54:11","date_gmt":"2022-11-28T20:54:11","guid":{"rendered":"https:\/\/voxzogohcp-dev-001.azurewebsites.net\/en-us\/voxzogo\/?page_id=61"},"modified":"2024-11-14T01:18:23","modified_gmt":"2024-11-14T01:18:23","slug":"voxzogo-safety","status":"publish","type":"page","link":"https:\/\/www.voxzogo.com\/en-us\/voxzogo-safety\/","title":{"rendered":"VOXZOGO Safety"},"content":{"rendered":"<div id=\"acf-block-6668b1037650d\" class=\"block wrapped-content bg-band bg-band-secondary block-zero-top block-tight-bottom\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6668b10376680\" class=\"block-wysiwyg\">\n            <h1 style=\"margin-bottom:0rem\">The Safety Of VOXZOGO Was Studied In 2 Robust Clinical Studies<\/h1>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-63f60235e21ec\" class=\"block wrapped-content block-zero-top\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-63f60235e2203\" class=\"block-wysiwyg\">\n            <h2>It&#x2019;s important to know:<\/h2>\n<ul>\n<li>VOXZOGO may cause serious <span class=\"glossaryLink\"  aria-describedby=\"tt\"  data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;Side effects&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;&amp;lt;!-- wp:paragraph --&amp;gt;also known as &amp;quot;adverse reactions,&rdquo; these are unwanted or undesired complications that can arise from a medication. They can be minor or more severe.&amp;lt;br\/&amp;gt;&amp;lt;!-- \/wp:paragraph --&amp;gt;&lt;\/div&gt;\"  data-mobile-support=\"0\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex='0' role='link'>side effects<\/span>, including a temporary decrease in blood pressure in some children<\/li>\n<li>You can reduce the risk of decreased blood pressure and associated symptoms (dizziness, feeling tired, or nausea) by following these steps in the hour prior to receiving VOXZOGO:\n<ul>\n<li><strong>Be well fed <\/strong><\/li>\n<li><strong>Be well hydrated<\/strong><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-63f60235e21ec\" class=\"block wrapped-content block-zero-bottom\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-63f60235e2203\" class=\"block-wysiwyg\">\n            <h2>These side effects were observed in children aged 5 to 15.<\/h2>\n<p>This table shows the number (n) of patients who experienced the most common side effects seen in more than 10% of VOXZOGO&#xAE; (vosoritide) patients over 1 year in a clinical trial*<\/p>\n    <\/div>\n\n<figure id=\"acf-block-66681a47c71d4\">\n    <div class=\"image image-rounded image-align-left\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/www.voxzogo.com\/en-us\/wp-content\/uploads\/sites\/5\/2024\/06\/BVOX_PatWebSite_SideEffects_Graphic_4.png?v=0.149\" alt=\"Table listing the most common side effects observed in children aged 5 to 15.\"\/>            <\/div>\n    <\/figure>\n\n<div id=\"acf-block-66681a47c7202\" class=\"block-wysiwyg\">\n            <p style=\"color: #707070;font-size: .8rem\">*Includes adverse reactions occurring in over 10% of VOXZOGO patients and more frequently in the VOXZOGO arm with a risk difference of &ge;5% (ie, difference of &gt;2 subjects) between treatment arms.<br>\n<sup>&#x2020;<\/sup>Injection site reactions occurring more frequently in VOXZOGO-treated subjects than placebo.<br>\n<sup>&#x2021;<\/sup>Includes the preferred terms: gastroenteritis and gastroenteritis, viral.<\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-63f60235e21ec\" class=\"block wrapped-content block-zero-bottom\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-63f60235e2203\" class=\"block-wysiwyg\">\n            <h2>The overall safety profile of VOXZOGO in children under the age of 5 was similar to that seen in children aged 5 and up.<\/h2>\n<p>The most common side effects seen in over 10% of VOXZOGO<sup>&#xAE;<\/sup> (vosoritide) patients under 5 years of age were injection site reactions (86%) and rash (28%).<\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-666759e2d5f38\" class=\"block boxed-content block-tight-top block-tight-bottom\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\">\n\t\t\t\t\t\t\t\t\n<div id=\"acf-block-66680009bfb50\" class=\"block-wysiwyg\">\n            <h2>97% of children aged 5 to 15 (58\/60) continued to take VOXZOGO after 1 year<sup>&#xA7;<\/sup><\/h2>\n    <\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-63f60235e21ec\" class=\"block wrapped-content block-zero-top\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-66681a47c730f\" class=\"block-wysiwyg\">\n            <p style=\"color: #707070;font-size: .8rem\"><sup>&#xA7;<\/sup>1 child discontinued due to injection pain, and 1 child discontinued due to fear of needles.<\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-66682eba14268\" class=\"block wrapped-content bg-band bg-band-secondary block-tight-top block-zero-bottom\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-66682eba1428e\" class=\"block-wysiwyg\">\n            <h4>Learn more about how to give VOXZOGO to your child.<\/h4>\n<p><a class=\"button button-arrow\" href=\"https:\/\/www.voxzogo.com\/en-us\/giving-voxzogo-to-your-child\/\" target=\"_self\">Get more details<\/a><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-6673ed165591e\" class=\"block wide-call-to-action block-tight-top block-zero-top block-tight-bottom block-zero-bottom\">\n    <div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"cta-content\">\n                                    <div class=\"title-block\">\n                        <h2>Have additional questions?<\/h2>\n                    <\/div>\n                                <div class=\"content-block\">\n                                            <h3>Have a local BioMarin Representative connect with you.<\/h3>\n                                                                \n                        <p><a class=\"button button-ghost button-arrow\" href=\"https:\/\/www.voxzogo.com\/en-us\/connect-with-a-rep\/\" target=\"_self\">Connect With a Rep<\/a><\/p>\n                                    <\/div>\n            <\/div>            \n\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-61","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>VOXZOGO\u00ae (vosoritide) | Safety &amp; 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