{"id":6409,"date":"2026-04-29T11:43:38","date_gmt":"2026-04-29T11:43:38","guid":{"rendered":"https:\/\/voxzogopatient-pprd-001.azurewebsites.net\/en-us\/?page_id=6409"},"modified":"2026-06-10T09:57:11","modified_gmt":"2026-06-10T09:57:11","slug":"clinical-results","status":"publish","type":"page","link":"https:\/\/www.voxzogo.com\/en-us\/clinical-results\/","title":{"rendered":"Clinical Results"},"content":{"rendered":"<div id=\"acf-block-6668b1037650d\" class=\"block wrapped-content bg-band bg-band-white block-zero-top block-tight-bottom block-remove-bottom-padding\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6668b10376680\" class=\"block-wysiwyg\">\n            <h1>Results with VOXZOGO<\/h1>\n<h2>Children with achondroplasia grew faster on VOXZOGO than without treatment<\/h2>\n<p>In a <span class=\"\"  data-mobile-support=\"0\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex='0' role='link'>clinical trial<\/span> of children aged 5 to 15 years, the impact of <span class=\"\"  data-mobile-support=\"0\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex='0' role='link'>VOXZOGO<\/span> on linear growth was measured over 1 year.<\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69fb53ec9ee45\" class=\"block wrapped-content block-tight-top\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-69fb53ec9f090\" class=\"block-wysiwyg\">\n            <p style=\"color: #c6007e;text-align: center\"><strong>Growth rate before and after 1 year of treatment<\/strong><\/p>\n    <\/div>\n\n<figure id=\"acf-block-69fb53ec9f30b\">\n    <div class=\"image image-responsive image-align-left\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/www.voxzogo.com\/en-us\/wp-content\/uploads\/sites\/5\/2026\/04\/Results_before-after-desktop.png?v=0.172\" alt=\"Bar chart showing greater annual growth rate with VOXZOGO vs placebo after 1 year\"\/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/www.voxzogo.com\/en-us\/wp-content\/uploads\/sites\/5\/2026\/05\/AGV_Chart_Simplified_CGBrochure_v3-02-mobile.png?v=0.172\" alt=\"Bar chart showing greater annual growth rate with VOXZOGO vs placebo after 1 year\"\/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69fb53ec9f54d\" class=\"block call-to-action vox-cta gradient\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box\">\n                <div class=\"vox-cta-content\">\n                                        \n                                        \n                                            <h2 style=\"text-align: center\"><span style=\"color: #ffffff\">Improvement in linear growth rate over baseline (from when treatment was started) was maintained over 4 years in an ongoing study.<\/span><\/h2>\n<p style=\"text-align: center\"><span style=\"color: #ffffff\">At year 4, the rate of growth was 1.88 in\/yr.<sup>&#x2020;<\/sup><\/span><\/p>\n                                        \n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69fb53ec9f5ac\" class=\"block wrapped-content\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-69fb53ec9f5e8\" class=\"block-wysiwyg\">\n            <h3 style=\"color: #685bc7;text-align: center\">97% of children (58\/60) stayed on VOXZOGO during the first year.<sup>&#x2021;<\/sup><\/h3>\n<p><small>*The difference when accounting for group characteristics, including sex and Tanner stage, treatment, <span class=\"\"  data-mobile-support=\"0\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex='0' role='link'>baseline<\/span> age, baseline growth rate, and baseline height Z-score.<\/small><br>\n<small><sup>&#x2020;<\/sup>These results are from the long-term follow-up study of the same clinical trial (known as an open-label extension), which did not have a <span class=\"\"  data-mobile-support=\"0\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex='0' role='link'>placebo group<\/span>, and caregivers, patients, and doctors were aware that all children were given VOXZOGO.<\/small><br>\n<small><sup>&#x2021;<\/sup>One child discontinued due to injection pain, and one child discontinued due to fear of needles.<\/small><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69fb53ec9f62d\" class=\"block wrapped-content bg-band bg-band-primary\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<figure id=\"acf-block-69fb53ec9f66f\">\n    <div class=\"image image-responsive image-rounded image-align-left\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/www.voxzogo.com\/en-us\/wp-content\/uploads\/sites\/5\/2026\/06\/meet-annika-new-1900x1006.png\" alt=\"Annika at ages 6 and 14, illustrating growth progress before and after taking VOXZOGO\"\/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/www.voxzogo.com\/en-us\/wp-content\/uploads\/sites\/5\/2026\/05\/Annika-image-mobile.png?v=0.172\" alt=\"Annika at ages 6 and 14, illustrating growth progress before and after taking VOXZOGO\"\/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n\n<div id=\"acf-block-69fb53ec9f690\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">Hear more stories like Annika&#x2019;s<\/h2>\n<p style=\"text-align: center\"><a class=\"button button-arrow\" href=\"https:\/\/www.voxzogo.com\/en-us\/patient-stories\/\">Watch Their Stories<\/a><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69fb5889403ef\" class=\"block wrapped-content\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-69fb58894042b\" class=\"block-wysiwyg\">\n            <h2>The impact of VOXZOGO continues to be studied<\/h2>\n<p>VOXZOGO is approved under accelerated approval based on an improvement in growth rate after 1 year of treatment. Compared to untreated patients in the study, <span class=\"\"  data-mobile-support=\"0\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex='0' role='link'>body proportionality<\/span> did not worsen at 1 year.<\/p>\n<p>Because <span class=\"\"  data-mobile-support=\"0\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex='0' role='link'>achondroplasia<\/span> is a condition that affects multiple aspects of physical development, <strong>additional studies on the impact of <span class=\"\"  data-mobile-support=\"0\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex='0' role='link'>VOXZOGO<\/span> over a longer period of time are ongoing, including its effects on final adult height and <span class=\"\"  data-mobile-support=\"0\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]' tabindex='0' role='link'>body proportionality<\/span>.<\/strong><\/p>\n    <\/div>\n\n<figure id=\"acf-block-69fb588940472\">\n    <div class=\"image image-responsive image-align-left\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/www.voxzogo.com\/en-us\/wp-content\/uploads\/sites\/5\/2026\/05\/clinical-trials-charts-1.png?v=0.172\" alt=\"Graphic comparing clinical trial results between 4 months to\"\/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/www.voxzogo.com\/en-us\/wp-content\/uploads\/sites\/5\/2026\/05\/clinical-trials-charts-mobile.png?v=0.172\" alt=\"Graphic comparing clinical trial results between 4 months to\"\/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n\n<div id=\"acf-block-69fb588940490\" class=\"block-wysiwyg\">\n            <p><small>*Visit clinicaltrials.gov for the complete list of the trials&#x2019; additional study measures (NCT03583697, NCT03989947, NCT03197766, NCT03424018).<\/small><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69fb5889404cf\" class=\"block wrapped-content bg-band bg-band-primary\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-69fb5889404ec\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">10+ years of clinical trial experience in achondroplasia<\/h2>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69fb5889407c4\" class=\"block call-to-action vox-cta magenta\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box\">\n                <div class=\"vox-cta-content\">\n                                        \n                                            <h3>Create a routine with your family<\/h3>\n                                        \n                                            <p>VOXZOGO can fit into your daily life.<\/p>\n                                        \n                                            <a href=\"https:\/\/www.voxzogo.com\/en-us\/maintaining-a-routine\/\" class=\"button button-text button-graphic\" target=\"\">\n                            <img decoding=\"async\" class=\"icon\" src=\"https:\/\/www.voxzogo.com\/en-us\/wp-content\/uploads\/sites\/5\/2026\/05\/routine.svg\" alt=\"\"\/>                            See How                        <\/a>\n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69fb588940b97\" class=\"block wide-call-to-action\">\n    <div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"cta-content\">\n                                    <div class=\"title-block\">\n                        <h2>Looking for more information about VOXZOGO?<\/h2>\n                    <\/div>\n                                <div class=\"content-block\">\n                                            <p>Your local BioMarin representative can help you find answers.<\/p>\n                                                                \n                        <p><a class=\"button button-ghost button-arrow\" href=\"https:\/\/www.voxzogo.com\/en-us\/connect-with-a-rep\/\" target=\"_self\">Connect Now<\/a><\/p>\n                                    <\/div>\n            <\/div>            \n\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-6409","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>VOXZOGO\u00ae Results: Bone Growth in Children with Achondroplasia<\/title>\n<meta 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