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Frequently asked questions
Find quick answers to common questions
How can VOXZOGO help my child?
VOXZOGO is indicated to increase linear growth in children with achondroplasia aged 5 years and up whose growth plates are still open. See the results in children receiving VOXZOGO in the clinical trial.
What should I know about VOXZOGO safety?
The safety profile of VOXZOGO has been studied over 1 year of treatment compared with placebo. Talk to your child’s doctor about the potential side effects.
Learn about the side effects from the clinical trial.
How does VOXZOGO work?
Achondroplasia affects endochondral bone growth—this is bone growth that replaces cartilage with bone tissue as your child grows. A balance between fibroblast growth factor receptor 3 (FGFR3) and C-type natriuretic peptide (CNP) signaling pathways occurs within the cells in the growth plate. FGFR3 slows bone growth while CNP promotes bone growth.
Achondroplasia is caused by an imbalance between FGFR3 and CNP signaling pathways and leads to impaired bone growth. Learn how VOXZOGO targets the imbalance to promote growth.
How do I get my child started with VOXZOGO?
Once your doctor decides that VOXZOGO is right for your child, you can follow these steps to get started or request to connect with a local BioMarin representative.
How can I find a local doctor for my child?
If you are interested in speaking with a healthcare provider who cares for children with achondroplasia, use the Achondroplasia Doctor Finder to find someone in your area.
How will I know how to administer VOXZOGO?
A healthcare provider will train you on how to give your child VOXZOGO at home. A BioMarin Clinical Coordinator is also available for injection training support and ongoing education.
In addition, we have resources, like videos and pamphlets, to help guide you throughout treatment.
Watch a step-by-step training video for how to inject VOXZOGO.
What is the age cutoff for starting my child on VOXZOGO?
VOXZOGO is indicated for increasing linear growth in children with achondroplasia aged 5 years and up with open growth plates. As long as growth plates are open, there is an opportunity for bone growth. In the clinical trial, some children who received VOXZOGO were up to 15 years old. Talk to your doctor who can determine potential for growth.
How long will my child take VOXZOGO?
VOXZOGO helps to improve annualized growth velocity in children with achondroplasia aged 5 years and older while their growth plates are open.
Regular checkups with your child’s prescribing doctor will be able to determine when their growth potential has been reached, and your child’s doctor will stop treatment when growth plates are closed. In the clinical trial, some children receiving VOXZOGO were up to 15 years old.
How do I get my child involved?
Download the Talking to Your Child About VOXZOGO guide for guidance on how to get your child involved in treatment.
Once you and your doctor decide VOXZOGO is right for your child, BioMarin RareConnections™ will reach out to discuss your insurance coverage and help you navigate your financial options for gaining access to treatment. Learn how we help.
Are there support resources available to help my family while on treatment?
BioMarin is committed to providing resources and support throughout your treatment. In addition to understanding insurance and financial assistance, you’ll also have a Clinical Coordinator who will provide one-to-one product education and injection training tailored to your family’s needs.