This website is intended for residents of the U.S. interested in achondroplasia or VOXZOGO
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Giving your child VOXZOGO

A routine that can fit into your daily life

VOXZOGO is an at-home daily injection given with a short, thin needle—smaller than the one used for most vaccinations.

Your child’s doctor will train you on how to give VOXZOGO and your BioMarin Clinical Coordinator will be available to reinforce training.

While routine vaccinations, like a flu shot, go into the muscle, VOXZOGO is given just under your child’s skin.

Caregiver preparing to administer a VOXZOGO subcutaneous injection to a young child with achondroplasia
Diagram comparing a standard vaccine needle to the smaller VOXZOGO needle used for subcutaneous injection

This image is not intended to show injection technique. Always refer to the Instructions for Use when giving VOXZOGO to your child.

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Lean on your Clinical Coordinators for help

You’ll be paired with a BioMarin Clinical Coordinator throughout the duration of your child’s treatment who will give one-to-one support with:

  • Providing product education and training on the injection process
  • Helping to find an injection routine that works for your family throughout your child’s entire time on treatment
  • Assisting through the specialty pharmacy process and sharing reminders for product refills
  • Offering flexible meeting options, including in person, virtually, or by email, phone, or text

Care and dosing information you should know

Inject VOXZOGO once daily, at about the same time

If a dose is missed,
it can be given within 12 hours. After 12 hours, skip the missed dose and administer the next daily dose.

The dose of
VOXZOGO is based
on body weight

Your healthcare provider will adjust the dose based
on weight changes at regular check-ups.

Stop VOXZOGO if instructed by your healthcare provider

Your healthcare provider will monitor your child’s growth and tell you when to stop VOXZOGO if your child’s bones are done growing.

Ahmin at ages 9 and 17 after completing VOXZOGO treatment, illustrating growth until growth plate closure
Ahmin at ages 9 and 17 after completing VOXZOGO treatment, illustrating growth until growth plate closure

Hear more stories like Ahmin’s

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One-to-one support

Clinical Coordinators are here to help throughout treatment.

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Looking for more information about VOXZOGO?

Your local BioMarin representative can help you find answers.

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IMPORTANT SAFETY INFORMATION

What is the most important safety information about VOXZOGO?

  • VOXZOGO may cause serious side effects including a temporary decrease in blood pressure in some patients. To reduce the risk of a decrease in blood pressure and associated symptoms (dizziness, feeling tired, or nausea), patients should eat a meal and drink 8 to 10 ounces of fluid within 1 hour before receiving VOXZOGO.

What are the most common side effects of VOXZOGO?

  • The most common side effects of VOXZOGO include injection site reactions (including redness, itching, swelling, bruising, rash, hives, and injection site pain), high levels of blood alkaline phosphatase shown in blood tests, vomiting, joint pain, decreased blood pressure, and stomach ache. These are not all the possible side effects of VOXZOGO. Ask your healthcare provider for medical advice about side effects, and about any side effects that bother the patient or that do not go away.

How is VOXZOGO taken?

  • VOXZOGO is taken daily as an injection given under the skin, administered by a caregiver after a healthcare provider determines the caregiver is able to administer VOXZOGO. Do not try to inject VOXZOGO until you have been shown the right way by your healthcare provider. VOXZOGO is supplied with Instructions for Use that describe the steps for preparing, injecting, and disposing VOXZOGO. Caregivers should review the Instructions for Use for guidance and any time they receive a refill of VOXZOGO in case any changes have been made.
  • Inject VOXZOGO 1 time every day, at about the same time each day. If a dose of VOXZOGO is missed, it can be given within 12 hours from the missed dose. After 12 hours, skip the missed dose and administer the next daily dose as usual.
  • The dose of VOXZOGO is based on body weight. Your healthcare provider will adjust the dose based on changes in weight following regular check-ups.
  • Your healthcare provider will monitor the patient’s growth and tell you when to stop taking VOXZOGO if they determine the patient is no longer able to grow. Stop administering VOXZOGO if instructed by your healthcare provider.

What should you tell the doctor before or during taking VOXZOGO?

  • Tell your doctor about all of the patient’s medical conditions including
    • If the patient has heart disease (cardiac or vascular disease), or if the patient is on blood pressure medicine (anti-hypertensive medicine).
    • If the patient has kidney problems or renal impairment.
    • If the patient is pregnant or plans to become pregnant. It is not known if VOXZOGO will harm the unborn baby.
    • If the patient is breastfeeding or plans to breastfeed. It is not known if VOXZOGO passes into breast milk.
  • Tell your doctor about all of the medicines the patient takes, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

You may report side effects to BioMarin at 1-866-906-6100. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see additional safety information in the full Prescribing Information and Patient Information.

What is VOXZOGO used for?

  • VOXZOGO is a prescription medicine used to increase linear growth in children with achondroplasia and open growth plates (epiphyses).
  • VOXZOGO is approved under accelerated approval based on an improvement in annualized growth velocity. Continued approval may be contingent upon verification and description of clinical benefit in confirmatory trials.